Live in the Chicago area currently and for the next six months.

Be able to receive text messages on your phone.Be of Chinese, Korean, or Vietnamese heritage.Be a woman between the ages of 18 and 45.If you are interested in being a participant you must qualify in every item below: A short telephone survey is conducted in the middle of the study. All participants receive $25 for each survey and hair collection session ($50 total for the study). All participants complete a survey and give a small hair sample at the beginning and end of the study. The “control” participants receive text messages only once a month. The “intervention” participants receive text messages several times a week to remind them about healthy foods. There are two types of participants in this study. We are collecting information from participants about their diets, and we’re taking small samples of hair for measurement of pollutants that might be in the food they eat. In this project we want to promote eating healthy foods while avoiding foods that carry pollutants. Zhang JZ, Lu TW, Stolerman LM, Tenner B, Yang J, Zhang JF, Falcke M, Rangamani P, Taylor SS, Mehta S, Zhang J.Welcome to Fish Intervention Study for Health Zhou X, Zhong Y, Molinar-Inglis O, Kunkel MT, Chen M, Sun T, Zhang J, Shyy JY, Trejo J, Newton AC, and Zhang J., Location-specific inhibition of Akt reveals regulation of mTORC1 activity in the nucleus. Spatially compartmentalized phase regulation of a Ca 2+-cAMP-PKA oscillatory circuit. Tenner B, Getz M, Ross B, Ohadi D, Bohrer CH, Greenwald E, Mehta S, Xiao J, Rangamani P †, and Zhang J †. An ultrasensitive biosensor for high-resolution kinase activity imaging in awake mice. Zhang JF*, Liu B*, Hong I*, Mo A, Roth RH, Tenner B, Lin W, Zhang JZ, Molina RS, Drobizhev M, Hughes TE, Tian L, Huganir RH †, Mehta S †, and Zhang J †.

Biochemical activity architectures visualized – Using genetically encoded fluorescent biosensors to map the spatial boundaries of signaling compartments. FluoSTEPs: Fluorescent biosensors for monitoring compartmentalized signaling within endogenous microdomains. Tenner B*, Zhang JZ*, Kwon Y, Pessino V, Feng S, Huang B, Mehta S †, and Zhang J †. Combing genetically encoded fluorescent biosensors, superresolution imaging, targeted biochemical perturbations and mathematic modeling, the Zhang laboratory is investigating the spatiotemporal regulation of cAMP/PKA, Ca 2+/calcineurin, PI3K/Akt/mTOR, Ras/ERK and AMPK pathways, in the context of energy metabolism, axon polarization and genesis, insulin secretion by β cells as well as tumorigenesis. It has been increasingly clear that the key lies in the spatiotemporal information encoded in a particular cellular context. We are investigating the molecular mechanisms and functional roles of such spatiotemporal regulation by taking a “native biochemistry” approach. This allows us to unravel chemical mechanisms of life processes in the framework of cellular time and space, where molecular changes can be directly linked to functional effects. Less well developed is our understanding of how these components are precisely regulated to achieve the functional specificity within a living cell, which may be simultaneously reacting to multiple inputs from the changing environment. The past decades have seen tremendous progress in identifying the molecular components that constitute the structural, biochemical and mechanical networks that control various life processes.

Our ultimate goal is to understand how cells, the basic units of life, sense changing environments and orchestrate specific responses to carry out life processes.

Jing zhang illinois